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yes and no. You can generate the “raw” sensitivities (bumping zero rates, hazard rates, optionlet vols etc.) in ORE with the ISDA required bucket structure.
But then you need to convert these into par sensitivities (Swap rates, CDS Spreads, flat Cap vols etc.). This does not work out of the box by means of configuring ORE. We have developed an additional converter that builds the Jacobi matrix and does the transformation. Or you take another approach bumping input market quotes and run ORE repeatedly, but this is inefficient unless you do some development in ORE.
So in both cases, you need to do some development to produce a CRIF.
I hope that helps.